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Details
Reputable manufacturer supply 3-(p-fluorophenyl)-3-phenylpropionic acid 362-86-7 in stock with high standard
- Molecular Formula: C15H13 F O2
- Molecular Weight: 244.265
- Vapor Pressure: 8.35E-06mmHg at 25°C
- Boiling Point: 359.8°Cat760mmHg
- Flash Point: 171.4°C
- PSA： 37.30000
- Density: 1.212g/cm3
- LogP: 3.43230
3-(p-fluorophenyl)-3-phenylpropionic acid(Cas 362-86-7) Usage
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General Description |
3-(p-fluorophenyl)-3-phenylpropionic acid, also known as flurbiprofen, is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used for its analgesic and anti-inflammatory properties. It works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and inflammation. Flurbiprofen is often used to treat conditions such as arthritis, menstrual cramps, and other types of pain. It is available in both prescription and over-the-counter forms, and is generally well tolerated when used as directed, although it may cause side effects such as gastrointestinal discomfort and increased risk of cardiovascular events with prolonged use. It is important to use flurbiprofen as directed and to consult a healthcare professional before using it, especially if you have any underlying health conditions or are taking other medications. |
InChI:InChI=1/C15H13FO2/c16-13-8-6-12(7-9-13)14(10-15(17)18)11-4-2-1-3-5-11/h1-9,14H,10H2,(H,17,18)
362-86-7 Relevant articles
Photoredox Activation of Formate Salts: Hydrocarboxylation of Alkenes via Carboxyl Group Transfer
Huang, Yan,Hou, Jing,Zhan, Le-Wu,Zhang, Qian,Tang, Wan-Ying,Li, Bin-Dong
, p. 15004 - 15012 (2021/12/14)
A photoredox activation mode of formate ...
Covalent organic framework supported Pd(II)-catalyzed conjugate additions of arylboronic acids to α,β-unsaturated carboxylic acids
Wen, Min,Lu, Shujuan,Fan, Chaogang,Shen, Kai,Lin, Shaohui,Pan, Qinmin
, (2021/04/28)
A palladium(II)-coordinated covalent org...
Synthesis method of succinic acid derivative or 3 -arylpropionic acid (by machine translation)
-
Paragraph 0101-0114; 0115; 0146, (2020/10/30)
The invention discloses a synthesis meth...
Cationic Pd(II)/bipyridine-catalyzed conjugate addition of arylboronic acids to α,β-unsaturated carboxylic acids in aqueous media
Ni, Yuxin,Song, Kaixuan,Shen, Kai,Yang, Zhenyu,Liu, Rui,Lin, Shaohui,Pan, Qinmin
supporting information, p. 1192 - 1195 (2018/03/01)
An in-situ generated cationic Pd(II)/bip...
362-86-7 Process route
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390-42-1
(E/Z)-3-(4-fluorophenyl)-3-phenylpropenoic acid
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-
362-86-7
3-(4-fluorophenyl)-3-phenylpropanoic acid
| Conditions | Yield |
|---|---|
|
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
at 20 ℃;
for 24h;
under 3750.38 Torr;
|
96%
|
|
With
Pd-BaSO4; ethanol;
Hydrogenation;
|
|
|
With
sodium hydroxide; sodium amalgam;
|
-
-
140-10-3
(E)-3-phenylacrylic acid
-
-
1765-93-1
4-fluoroboronic acid
-
-
362-86-7
3-(4-fluorophenyl)-3-phenylpropanoic acid
| Conditions | Yield |
|---|---|
|
With
dichloro(2,2'-bipyridine)palladium(II); silver nitrate;
In
water;
at 60 ℃;
for 12h;
Green chemistry;
|
96%
|
362-86-7 Upstream products
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462-06-6
fluorobenzene
-
140-10-3
(E)-3-phenylacrylic acid
-
390-42-1
(E/Z)-3-(4-fluorophenyl)-3-phenylpropenoic acid
-
365-21-9
1-(chlorophenylmethyl)-4-fluorobenzene
362-86-7 Downstream products
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85662-85-7
3-(4-fluorophenyl)-2,3-dihydro-1H-indene-1-one
-
374724-94-4
3-(4-fluorophenyl)-3-phenylpropan-1-ol
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80272-55-5
cis-3-(4-fluorophenyl)-2,3-dihydro-1H-inden-1-ol
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104087-10-7
1-chloro-4-(4-flurophenyl)indan
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