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Details
Factory Supply Industrial Grade 4-Methyl-5-imidazolemethanol hydrochloride 38585-62-5 with Best Price
- Molecular Formula: C5H9ClN2O
- Molecular Weight: 148.592
- Appearance/Colour: off-white solid powder eyeballing
- Melting Point: 231-235 °C
- Boiling Point: 389.1 °C at 760 mmHg
- Flash Point: 189.1 °C
- PSA： 48.91000
- LogP: 1.01240
4-Methyl-5-imidazolemethanol hydrochloride(Cas 38585-62-5) Usage
InChI:InChI=1/C5H8N2O.ClH/c1-4-5(2-8)7-3-6-4;/h3,8H,2H2,1H3,(H,6,7);1H
38585-62-5 Relevant articles
Design, synthesis and evaluation of small molecule CD4-mimics as entry inhibitors possessing broad spectrum anti-HIV-1 activity
Curreli, Francesca,Belov, Dmitry S.,Ramesh, Ranjith R.,Patel, Naisargi,Altieri, Andrea,Kurkin, Alexander V.,Debnath, Asim K.
, p. 5988 - 6003 (2016)
Since our first discovery of a CD4-mimic...
Importance of the azole moiety of cimetidine derivatives for the inhibition of human multidrug and toxin extrusion transporter 1 (hmate1)
Shinya, Susumu,Kawai, Kentaro,Tarui, Atsushi,Karuo, Yukiko,Sato, Kazuyuki,Matsuda, Masaya,Kitatani, Kazuyuki,Kobayashi, Naoki,Nabe, Takeshi,Otsuka, Masato,Omote, Masaaki
, p. 905 - 912 (2021/09/06)
Herein, we describe the design and synth...
Process for the manufacture of 4-methyl-5-hydroxymethyl-imidazole
-
, (2008/06/13)
A process is provided for the manufactur...
The sodium/ammonia reduction of 5-ethoxycarbonyl-4-methylimidazole: A key intermediate in the synthesis of cimetidine
Wellman,Mendelson,Lam,et al.
, p. 356 - 358 (2007/10/02)
-
38585-62-5 Process route
-
-
50-00-0,30525-89-4,61233-19-0
formaldehyd
-
-
822-36-6,872-33-3
4-Methylimidazole
-
-
38585-62-5
4-hydroxymethyl-5-methylimidazole hydrochloride
| Conditions | Yield |
|---|---|
|
formaldehyd; 4-Methylimidazole;
With
potassium carbonate;
In
isopropyl alcohol;
at 55 ℃;
for 19h;
Inert atmosphere;
With
hydrogenchloride;
In
water;
at 20 ℃;
for 1h;
|
53%
|
-
-
60-29-7,927820-24-4
diethyl ether
-
-
51605-32-4
Ethyl 5-Methyl-4-imidazolecarboxylate
-
-
38585-62-5
4-hydroxymethyl-5-methylimidazole hydrochloride
| Conditions | Yield |
|---|---|
|
With
ammonium chloride; sodium;
In
methanol; ethanol; ammonia; water; isopropyl alcohol; acetone;
|
94%
|
38585-62-5 Upstream products
-
123-91-1
1,4-dioxane
-
51605-32-4
Ethyl 5-Methyl-4-imidazolecarboxylate
-
60-29-7
diethyl ether
-
50-00-0
formaldehyd
38585-62-5 Downstream products
-
75613-67-1
Cyclohexyl-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-amine; hydrobromide
-
51605-33-5
4-chloromethyl-5-methyl-imidazole hydrochloride
-
122852-42-0
alosetron
-
128486-54-4
6-fluoro-2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)-methyl]-1H-pyrido[4,3-b]indol-1-one
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